Mentions légales
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| 14.07.2022 | AC d'Escaldes | 0-1 AET | Gzira United | |
| 05.07.2022 | Gzira United | 1-1 | AC d'Escaldes |
| 14.07.2022 | Akademija Pandev | 1-2 | Lechia Gdańsk | |
| 07.07.2022 | Lechia Gdańsk | 4-1 | Akademija Pandev |
| 14.07.2022 | Hamrun Spartans | 4-1 | Alashkert Martuni | |
| 07.07.2022 | Alashkert Martuni | 1-0 | Hamrun Spartans |
| 14.07.2022 | Ararat Yerevan | 2-2 | Shkendija'79 | |
| 07.07.2022 | Shkendija'79 | 2-0 | Ararat Yerevan |
| 14.07.2022 | Sligo Rovers | 0-1/p.4-3 | Bala Town | |
| 07.07.2022 | Bala Town | 1-2 | Sligo Rovers |
| 14.07.2022 | B36 Torshavn | 3-1/p.4-3 | Borac Banja Luka | |
| 07.07.2022 | Borac Banja Luka | 2-0 | B36 Torshavn |
| 14.07.2022 | Breidablik | 4-1 | UE Santa Coloma | |
| 07.07.2022 | UE Santa Coloma | 0-1 | Breidablik |
| 14.07.2022 | SP Tre Fiori | 3-1 | CS Fola Esch | |
| 07.07.2022 | CS Fola Esch | 0-1 | SP Tre Fiori |
| 14.07.2022 | Riga FC | 2-0 | Derry City | |
| 07.07.2022 | Derry City | 0-2 | Riga FC |
| 14.07.2022 | Decic Tuzi | 1-2 | Dinamo Minsk | |
| 07.07.2022 | Dinamo Minsk | 1-1 | Decic Tuzi |
| 14.07.2022 | Paide Linnameeskond | 1-2/p.6-5 | Dinamo Tbilisi | |
| 07.07.2022 | Dinamo Tbilisi | 2-3 | Paide Linnameeskond |
| 14.07.2022 | Cliftonville Belfast | 0-3 | Dunajska Streda | |
| 07.07.2022 | Dunajska Streda | 2-1 | Cliftonville Belfast |
| 14.07.2022 | FC Milsami | 2-0 | FK Panevezys | |
| 07.07.2022 | FK Panevezys | 0-0 | FC Milsami |
| 14.07.2022 | Crusaders Belfast | 3-1 | FCB Magpies | |
| 07.07.2022 | FCB Magpies | 2-1 | Crusaders Belfast |
| 14.07.2022 | FK Liepaja | 3-1 | Gjilani | |
| 07.07.2022 | Gjilani | 1-0 | FK Liepaja |
| 14.07.2022 | FK Tuzla City | 6-0 | SP Tre Penne | |
| 07.07.2022 | SP Tre Penne | 0-2 | FK Tuzla City |
| 14.07.2022 | Petrocub Hîncești | 1-0 | Floriana FC | |
| 07.07.2022 | Floriana FC | 0-0 | Petrocub Hîncești |
| 14.07.2022 | Newtown AFC | 2-1/p.4-2 | HB Torshavn | |
| 07.07.2022 | HB Torshavn | 1-0 | Newtown AFC |
| 12.07.2022 | Drita FC | 3-0 | Inter Turku | |
| 06.07.2022 | Inter Turku | 1-0 | Drita FC |
| 14.07.2022 | Iskra Danilovgrad | 0-1 | KF Laci | |
| 07.07.2022 | KF Laci | 0-0 | Iskra Danilovgrad |
| 14.07.2022 | KR Reykjavik | 1-0 | Pogoń Szczecin | |
| 07.07.2022 | Pogoń Szczecin | 4-1 | KR Reykjavik |
| 14.07.2022 | Dila Gori | 0-0 | KuPS Kuopio | |
| 07.07.2022 | KuPS Kuopio | 2-0 | Dila Gori |
| 14.07.2022 | Larne FC | 0-1 | St Joseph's (GIB) | |
| 05.07.2022 | St Joseph's (GIB) | 0-0 | Larne FC |
| 14.07.2022 | Llapi | 2-2 | FK Buducnost | |
| 07.07.2022 | FK Buducnost | 2-0 | Llapi |
| 14.07.2022 | FK Kauno Zalgiris | 0-0 | MFK Ruzomberok | |
| 07.07.2022 | MFK Ruzomberok | 2-0 | FK Kauno Zalgiris |
| 14.07.2022 | Differdange | 1-2 AET | Olimpija Ljubljana | |
| 07.07.2022 | Olimpija Ljubljana | 1-1 | Differdange |
| 14.07.2022 | Partizani Tirana | 0-1/p.4-5 | FC Iberia 1999 | |
| 07.07.2022 | FC Iberia 1999 | 0-1 | Partizani Tirana |
| 14.07.2022 | Seinajoen JK | 4-2 AET | Flora Tallinn | |
| 07.07.2022 | Flora Tallinn | 1-0 | Seinajoen JK |
| 14.07.2022 | Mura | 2-1 | Sfîntul Gheorghe | |
| 07.07.2022 | Sfîntul Gheorghe | 1-2 | Mura |
| 14.07.2022 | Europa FC | 1-2 | Vikingur Gøta | |
| 06.07.2022 | Vikingur Gøta | 1-0 | Europa FC |